Corona Virus: A 71-year-old Michigan woman returned from a Nile River cruise suffering from bloody diarrhea, abdominal pain, and vomiting. Her doctors initially suspected a stomach bug, but when she developed a cough and a nasal swab, they found that she had a novel coronavirus. Her stool sample was positive for viral RNA, and there were signs of colon injury. The coronavirus attacks several organs, including the brain, kidneys, and heart.
SARS-CoV-2 causes encephalitis
SARS-CoV-2 is a neurotropic, neuroinvasive virus that can cause encephalitis in humans. It has been found in infected individuals’ Cerebrospinal Fluid (CSF) and central nervous system. It has also been found in the brain and glial cells in post-mortem examinations.
SARS-CoV-2 infections usually manifest respiratory symptoms and fever, but neurological complications have been reported recently. A case of SARS-CoV-2 encephalitis was reported in Indonesia in March 2020. The patient’s CSF contained antibodies to the virus, which suggested that the virus was the cause of the disease. The patient’s immune system responded well to immunotherapy, which improved his condition.
Serum biomarkers can be used to identify patients with SARS-CoV-2 encephalitis and help to develop therapeutic strategies. ANGPTL4 is a neuronal marker that is elevated in SARS-CoV-2-infected patients.
Clinical and radiological signs of SARS-CoV-2
Clinical and radiological signs of SARS-CoV-2 encephalitis can be difficult to diagnose in infected patients. In these cases, additional examinations are necessary to rule out other conditions. An MRI of the brain, EEG monitoring, and lumbar puncture should be done if encephalitis is suspected.
PCR detection of the SARS-CoV-2 virus in CSF
PCR detection of the SARS-CoV-2 virus in CSF was limited in the initial investigation because of a lack of resources. However, a study that showed a positive PCR in one patient suggests that CSF involvement may have been secondary to the inflammatory phase of the infection. Additionally, the absence of inflammatory markers in CSF may affect the systemic inflammatory response.
Although the neurological manifestations of SARS-CoV-2 infection are still rare, a growing number of case reports describe a variety of symptoms in 901 patients. Those who developed primary respiratory infections from the infection weeks earlier may have developed neurological sequelae. Although these symptoms may not indicate severe CNS disease, they can provide a baseline for further research.
Corona virus attacks the kidney
Coronavirus (COV) infections have a severe effect on the kidneys. They can lead to kidney failure and other complications. Symptoms include high protein in the urine and abnormal blood work. Some patients may even require dialysis. Corona virus infection may also be associated with other underlying medical conditions, such as pneumonia.
Coronavirus is a novel coronavirus that has become a pandemic disease. About 5% of patients with this disease develop severe symptoms. The virus affects the kidneys by both direct and indirect mechanisms, which result in proteinuria and acute kidney injury. The pathogenesis of SARS-CoV-2-induced kidney damage is complex, but the infection has been associated with acute tubular necrosis, protein leakage from Bowman’s capsule, and mitochondrial dysfunction.
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About kidney and Corona virus
The kidney is a key organ system, removing toxins, excess water, and waste products from the blood. But the COVID-19 virus can damage the kidney by causing tiny clots in the bloodstream, clogging the smallest blood vessels in the kidney. This impairs the kidney’s ability to filter waste, resulting in severe illness and even death. Patients who are affected by COVID-19 often experience severe kidney damage, and about a third will not recover full kidney function.
Acute kidney injury is the most common manifestation of COVID-19, which mostly affects people aged thirty to 79. Most cases are mild, but some patients can develop progressive respiratory failure and alveolar damage. Six percent of patients develop fatalities. The pathogenesis of COVID-19 is not fully understood, but it is known that direct viral injury, uncontrolled inflammation, and complement cascades play a role. Acute kidney injury is usually accompanied by proteinuria, hematuria, and a slight elevation in creatinine.
In the presence of COVID-19 infection, kidney involvement is a common symptom. The disease is also associated with respiratory failure and hypoxemia, and histopathological findings suggest several potential pathways for the development of acute kidney injury. While COVID-related sepsis is often associated with severe kidney damage, SARS-CoV-2 infection can also cause acute kidney injury.
Corona virus attacks the heart
Corona virus infections can result in serious cardiovascular problems, such as heart attacks and strokes. The virus can affect any chamber of the heart, including the right ventricle, which pumps oxygen-poor blood to the lungs. Patients with pre-existing heart conditions may also be at risk for heart problems. Corona virus infection causes widespread inflammation in the body, which may further stress an already-weakened heart.
Coronavirus infections can cause inflammation of the heart muscle tissue, which can lead to blood clots. The virus also can affect small vessels, compromising blood flow. While coronavirus infection is rare, severe disease can result in heart failure. The virus is particularly dangerous for elderly people with high blood pressure and obesity.
Symptoms of COVID-19 infection may persist for four weeks or more. In such cases, healthcare providers may perform tests to assess the state of the heart and its function. Moreover, COVID-19 can affect various organs, including the brain and kidneys. In such a case, it is important to monitor your symptoms.
COVID-19 virus can directly infect
The COVID-19 virus can directly infect the heart muscle. Because it directly affects the heart, it increases the stress placed on the cardiovascular system. Inflammation of the heart tissue may result in severe COVID-19 symptoms, including respiratory failure, cardiac arrest, and arrhythmias. In addition, COVID-19 can cause a cytokine storm in the body, which may lead to organ failure.
As the number of infected people increases, the risk of heart disease rises. Cardiologists are urging people to monitor their heart health if symptoms of COVID-19 occur. Aside from causing heart failure, the disease can also cause myocarditis. The disease has a fatal outcome if left untreated.